Introducing MACI cartilage repair using your own cells
MACI is a procedure that repairs cartilage using the patient’s own cells. MACI provides long-lasting pain relief and improvement in function.1
How does MACI work?
A sample of your cartilage cells (chondrocytes) is sent to a laboratory and embedded on a special collagen membrane which your doctor then implants into your knee. The cartilage cells regenerate, forming a repair tissue that is able to fill the cartilage defect.
creates a repair tissue that allows patients to resume an active lifestyle¹
About the summit extension trial1
In the SUMMIT Trial, patients treated with MACI experienced statistically significantly greater outcomes versus microfracture including scores related to activities of daily living, quality of life, and overall knee condition.¹
The safety and long-term clinical benefit of MACI have only been studied in the knee joint. MACI has not been approved for use in joints other than the knee. The safety and effectiveness of MACI have not been proven for patients 55 years old and older.
1. Saris D, Price A, Widuchowski W, et al. Matrix-applied characterized autologous cultured chondrocytes versus microfracture: Two-year follow-up of a prospective randomized trial. Am J Sports Med. 2014;42(6):1384-94.