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MACI Myths: Debunking Three Knee Cartilage Repair Misconceptions

MACI Myths: Debunking Three Knee Cartilage Repair Misconceptions

Separate the facts from fiction when it comes to MACI knee cartilage repair. We debunk three common MACI myths.

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Reclaim the Moments That Matter by Treating Knee Cartilage Pain

Reclaim the Moments That Matter by Treating Knee Cartilage Pain

By effectively treating knee cartilage damage, patients sidelined by knee pain may be able to reclaim the moments that matter most.

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Why Move Forward with Knee Cartilage Repair After Arthroscopy

Why Move Forward with Knee Cartilage Repair After Arthroscopy

Cartilage damage does not heal on its own. An arthroscopy can provide temporary relief for people living with knee cartilage damage, but the pain often returns. MACI knee cartilage repair can provide lasting improvements to knee pain and function.

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Time Matters: Why You Shouldn't Wait to Treat Your Cartilage Injury

Time Matters: Why You Shouldn't Wait to Treat Your Cartilage Injury

A study found that patients undergoing cell-based knee cartilage repair who experienced a long delay between biopsy and implantation were at greater risk for cartilage defect expansion and the appearance of new defects.

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Indication and Important Safety Information

Important Safety Information

MACI should not be used if you:

  • are allergic to antibiotics such as gentamicin, or materials that come from cow, pig, or ox;
  • have severe osteoarthritis of the knee, other severe inflammatory conditions, infections or inflammation in the bone joint and other surrounding tissue, or blood clotting conditions;
  • have had knee surgery in the past 6 months, not including surgery for obtaining a cartilage biopsy or a surgical procedure to prepare your knee for a MACI implant;
  • or cannot follow a doctor-prescribed rehabilitation program after your surgery

Consult your doctor if you have cancer in the area of the cartilage biopsy or implant as the safety of MACI is not known in those cases.

Conditions that existed before your surgery, including meniscus tears, joint or ligament instability, or alignment problems should be evaluated and treated before or at the same time as the MACI implant.

MACI is not recommended if you are pregnant.

MACI has not been studied in patients younger than 18 or over 55 years of age.

Common side effects include joint pain, tendonitis, back pain, joint swelling, and joint effusion.

More serious side effects include joint pain, cartilage or meniscus injury, treatment failure, and osteoarthritis.

Please see Full Prescribing Information for more information.

Indication

MACI® is made up of your own (autologous) cells that are expanded and placed onto a film that is implanted into the area of the cartilage damage and absorbed back into your own tissue.

MACI® (autologous cultured chondrocytes on porcine collagen membrane) is made up of your own (autologous) cells that are expanded and placed onto a film that is implanted into the area of the cartilage damage and absorbed back into your own tissue.

MACI is used for the repair of symptomatic cartilage damage of the adult knee.

The amount of MACI applied depends on the size of the cartilage damage. The MACI film is trimmed by your surgeon to match the size and shape of the damage, to ensure the damaged area is completely covered.

Limitations of Use

It is not known whether MACI is effective in joints other than the knee.

It is not known whether MACI is safe or effective in patients over the age of 55 years.