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Time Matters: Why You Shouldn't Wait to Treat Your Cartilage Injury

Time Matters: Why You Shouldn't Wait to Treat Your Cartilage Injury

A study found that patients undergoing cell-based knee cartilage repair who experienced a long delay between biopsy and implantation were at greater risk for cartilage defect expansion and the appearance of new defects.

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Undergoing Knee Cartilage Repair? Here’s What You May Expect in the Early Days of Rehab.

Undergoing Knee Cartilage Repair? Here’s What You May Expect in the Early Days of Rehab.

Caroline Brunst, a board-certified physical therapist, answers some common questions that patients have about the early rehabilitation stage immediately following the MACI procedure.

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Arthroscopy Is the First Step for Durable Knee Cartilage Repair

Arthroscopy Is the First Step for Durable Knee Cartilage Repair

The first step in the MACI® (autologous cultured chondrocytes on porcine collagen membrane) knee cartilage repair journey is an arthroscopy.  This is is a minimally invasive, out-patient procedure that allows a surgeon to scope the knee and diagnose the causes of knee pain.

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How MACI Knee Cartilage Repair Got Kayla Back to an Active Life

How MACI Knee Cartilage Repair Got Kayla Back to an Active Life

Kayla grew up in a family where sports were central to everything. Then at age 12 — that all changed.

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Indication and Important Safety Information

Important Safety Information

MACI should not be used if you:

  • are allergic to antibiotics such as gentamicin, or materials that come from cow, pig, or ox;
  • have severe osteoarthritis of the knee, other severe inflammatory conditions, infections or inflammation in the bone joint and other surrounding tissue, or blood clotting conditions;
  • have had knee surgery in the past 6 months, not including surgery for obtaining a cartilage biopsy or a surgical procedure to prepare your knee for a MACI implant;
  • or cannot follow a doctor-prescribed rehabilitation program after your surgery

Consult your doctor if you have cancer in the area of the cartilage biopsy or implant as the safety of MACI is not known in those cases.

Conditions that existed before your surgery, including meniscus tears, joint or ligament instability, or alignment problems should be evaluated and treated before or at the same time as the MACI implant.

MACI is not recommended if you are pregnant.

MACI has not been studied in patients younger than 18 or over 55 years of age.

Common side effects include joint pain, tendonitis, back pain, joint swelling, and joint effusion.

More serious side effects include joint pain, cartilage or meniscus injury, treatment failure, and osteoarthritis.

Please see Full Prescribing Information for more information.

Indication

MACI® is made up of your own (autologous) cells that are expanded and placed onto a film that is implanted into the area of the cartilage damage and absorbed back into your own tissue. MACI is used for the repair of symptomatic cartilage damage of the adult knee.

MACI® (autologous cultured chondrocytes on porcine collagen membrane) is made up of your own (autologous) cells that are expanded and placed onto a film that is implanted into the area of the cartilage damage and absorbed back into your own tissue.

MACI is used for the repair of symptomatic cartilage damage of the adult knee.

The amount of MACI applied depends on the size of the cartilage damage. The MACI film is trimmed by your surgeon to match the size and shape of the damage, to ensure the damaged area is completely covered.

Limitations of Use

It is not known whether MACI is effective in joints other than the knee.

It is not known whether MACI is safe or effective in patients over the age of 55 years.